Fok1 and Col1A1 Gene Polymorphisms and Development of Treatment-Related Bone Complications in Children with Acute Lymphoblastic Leukemia: focus on molecular change
نویسندگان
چکیده
منابع مشابه
Expression of ROR1 Gene in Patients with Acute Lymphoblastic Leukemia
Background: Acute lymphoblastic leukemia (ALL) results from genetic alterations in a single lymphoid progenitor cell. Expression of ROR1 is reported to be increased in ALL and mantle cell lymphoma. In this study the expression of ROR1 was assessed in newly diagnosed patients with ALL. Methods: This study was carried out on 40 patients with newly diagnosed ALL and healthy individuals as contro...
متن کاملMonitoring and treatment of acute kidney injury in children with acute lymphoblastic leukemia after high dose methotrexate chemotherapy
Abstact：objective To investigate acute kidney injury (AKI) in children with acute lymphoblastic leukemia (ALL) who received high dose methotrexate (MTX) chemotherapy and explore the corresponding treatment. Methods 180 children who received high dose MTX chemotherapy were observed with serum MTX concentration and serum creatinine. Patients with AKI of stage 3 or poor response to conventional tr...
متن کاملMonitoring and treatment of acute kidney injury in children with acute lymphoblastic leukemia after high dose methotrexate chemotherapy
Abstact：objective To investigate acute kidney injury (AKI) in children with acute lymphoblastic leukemia (ALL) who received high dose methotrexate (MTX) chemotherapy and explore the corresponding treatment. Methods 180 children who received high dose MTX chemotherapy were observed with serum MTX concentration and serum creatinine. Patients with AKI of stage 3 or poor response to conventional tr...
متن کاملBone Mineral Density, Lean Body Mass and Bone Biomarkers Following Physical Exercise in Children with Acute Lymphoblastic Leukemia Undergoing Chemotherapy
Background: This study was aimed to evaluate the effects of physical exercise on bone mineral density (BMD), lean body mass (LBM) and bone biomarkers in children with acute lymphoblastic leukemia on chemotherapy. Methods: forty-six leukemic children were randomly assigned to two groups; exercise group (E) undergoing supervised mixed exercise program consisting of aerobic, resistance and flexib...
متن کاملBone Scintigraphy in Acute Lymphoblastic Leukemia
Leukemia is the most common childhood cancer and accounts for 30-40% of all malignancies. A retrospective review was performed of the hospital records of 9 children, 6 boys and 3 girls, aged from 2.5 to 15 years with ALL initially referred to Nemazee hospital Nuclear medicine center for whole body bone scanning between 2000 and 2002. Bone marrow pathology established ALL (L1) in two and ALL (...
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ژورنال
عنوان ژورنال: Turkish Journal of Hematology
سال: 2018
ISSN: 1300-7777
DOI: 10.4274/tjh.2018.0424